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Cardiovascular system and artificial replacements

Constitutive modeling of blood vessels

Project description:

Internal pressure-circumferential stretch relationship observed within inflation and extension of venous aorto-coronary bypass

Predictions of internal pressure within sample inflation based on found constitutive models for CABG tissue

Blood vessel walls exhibit complicated mechanical response to external loading; both material and geometrical nonlinearity, inelasticity and anisotropy are observed. Such complex behavior originates in internal structure and its arrangement (cellular and non-cellular components, layered character, fibrous arrangement, inter-component bonding). Efficient constitutive model which can capture not only observed phenomena but structural fundament as well is still in question.

Successful mathematical modeling involves experimental data describing material response. Tensile tests, inflation-extension tests and pressure-pulse tests are carried out in the laboratory.

Representative simulation of the inflation-extension response of male 38 years of age male abdominal aorta.


New constitutive model for soft tissues' mechanics and anistorpic elastomers based on limiting fiber extensibility>

Horny L, Netusil M, Daniel M. (2014) Limiting extensibility constitutive model with distributed fibre orientations and ageing of abdominal aorta. Journal of the Mechanical Bahavior of Biomedical Materials, accepted for publiation. DOI: 10.1016/j.jmbbm.2014.05.021   MANUSCRIPT

Hynek Chlup doc. Ing. Lukáš Horný Ph.D.Ing. Jakub Kronek Ph.D.


Department of Forensic Medicine 3rd Faculty of Medicine CUInstitute of Thermomechanics AS CR, vvi